Tzeng, N.S. et al. (2018)
Frontiers in Psychiatry, 9: 133

This Taiwanese study looked at 186,588 participants who had allergic diseases and 139,941 healthy control participants. They were selected from the Longitudinal Health Insurance Database (2000-2015) from the National Health Insurance Research Database. Researchers evaluated bronchial asthma, allergic rhinitis, atopic dermatitis, and combinations of these diseases. Interestingly, 10.8% of those with an allergic condition developed a psychiatric disorder, as opposed to 6.7% in the control group. Bronchial asthma in particular was associated with increased individual risk of dementia, anxiety disorders, depressive disorders, eating disorders, bipolar disorders, sleep disorders, and psychotic disorders. ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀
These findings are in line with previous studies on autoimmune diseases of overall allergic and atopic diseases being associated with psychiatric disorders. It’s also worth noting that the study found that oral prednisolone usage (anti-inflammatory corticosteroid) was associated with a lower risk of developing psychiatric disorders in those with bronchial asthma. ⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀⠀
Tzeng, N. S., et al. (2018). Increased risk of psychiatric disorders in allergic diseases: A nationwide, population-based, cohort study. Frontiers in Psychiatry. doi:10.3389/fpsyt.2017.00133